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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK1
All Species:
35.45
Human Site:
Y549
Identified Species:
78
UniProt:
Q9UKI8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKI8
NP_036422.3
766
86700
Y549
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Chimpanzee
Pan troglodytes
XP_001141231
787
89005
Y570
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Rhesus Macaque
Macaca mulatta
XP_001084145
718
81923
Y501
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Dog
Lupus familis
XP_535959
766
86670
Y549
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0V0
766
86605
Y549
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
Y501
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Chicken
Gallus gallus
XP_426581
764
86358
Y547
E
G
N
D
L
D
F
Y
L
K
Q
H
K
L
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90ZY6
756
85436
C535
F
C
T
V
L
E
F
C
E
G
N
D
L
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
Y562
D
G
H
D
L
D
F
Y
L
K
Q
H
K
T
I
Nematode Worm
Caenorhab. elegans
P34314
965
109255
Y744
P
G
N
D
L
D
F
Y
L
K
Q
N
R
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
L468
E
C
E
I
H
K
S
L
V
H
H
H
I
V
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.5
99.4
N.A.
98.1
N.A.
N.A.
91.5
94.1
N.A.
83.2
N.A.
N.A.
46.4
37.9
N.A.
Protein Similarity:
100
97.3
93.7
99.7
N.A.
99.2
N.A.
N.A.
92.8
95.8
N.A.
89.4
N.A.
N.A.
61.2
50.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
13.3
N.A.
N.A.
73.3
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
20
N.A.
N.A.
93.3
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
19
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
82
0
82
0
0
0
0
0
10
0
10
0
% D
% Glu:
73
0
10
0
0
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
91
0
0
0
0
0
0
0
10
% F
% Gly:
0
82
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
10
0
10
0
0
0
0
10
10
82
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
19
% I
% Lys:
0
0
0
0
0
10
0
0
0
82
0
0
73
0
0
% K
% Leu:
0
0
0
0
91
0
0
10
82
0
0
0
10
64
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
% M
% Asn:
0
0
73
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _